Botulinum toxin type A, a neurotoxic protein produced by the bacterium Clostridium botulinum, has revolutionized both medical and cosmetic industries. It is primarily known for its ability to temporarily paralyze muscles, making it highly effective in treating various medical conditions and aesthetic concerns. Among the numerous brands available, Botulax and Innotox stand out. This article provides an in-depth analysis of these two botulinum toxin products, highlighting their characteristics, differences, and potential applications.
Botulax and Innotox are both derived from botulinum toxin type A but are produced by different manufacturers. Botulax is produced by Hugel Inc., a South Korean pharmaceutical company established in 2001. Hugel has gained a strong reputation for its expertise in the field of biotechnology and medical aesthetics. Innotox, on the other hand, is manufactured by Medytox, another South Korean biopharmaceutical company founded in 2000. Medytox is known for pioneering various advanced biotechnological solutions and has been instrumental in the development of innovative botulinum toxin products.
Perhaps Botulax is one of the most recognizable Korean botulinum toxin around the world and rightfully can be called the best botulinum toxin products. Botulax is supplied as a lyophilized powder that requires reconstitution with saline before use.
Botulax has passed all the necessary clinical studies and is one of the analogues of drugs containing botulinum toxin type A. Botulax contains only three components - human albumin, botulinum toxin type A and saline. These substances are perfectly accepted by the body, there is no risk of rejection and therefore allergic reactions are excluded even theoretically.
The advantage of Botulax is the inability to penetrate into neighboring tissues due to its high molecular weight and medium concentration of albumin. Botulax is widely used to smooth mimic wrinkles and temporarily correct hyperhidrosis.
The first results after the introduction of Botulax can be assessed already on the 3rd day, and the maximum effect is achieved on the 14th day. Appearance after rejuvenation will be maintained for 4-6 months. Release form for 100 units and 200 units.
Innotox is an innovative premium preparation of botulinum toxin type A developed by the well-known South Korean company Medytox Inc. Meditox Inc. is one of the world’s largest and best biopharmaceutical companies and has won the respect of customers with its high quality products.
Unlike the world famous botulinum txoin, Innotox has a liquid dosage form (ready to use and does not require dilution) and an improved formula. It is popular in many countries of the world due to its ease of use, high efficiency and low cost.
Most often, Innotox is used to eliminate many cosmetic problems such as blepharospasm, hemifacial spasm, spastic torticollis, mimic wrinkles, bunny lines, excessive sweating of the palms and armpits, brow furrow, nasolabial folds, wrinkles around the mouth and meso treatment.
With the help of Innotox, you can correct the shape of the nose and face oval, correct errors in the position of the lips, expressed in the constant elevation of both parts.
The first result after Innotox treatment is visible after 3-5 days, the maximum effect is achieved after a couple of weeks and lasts up to six months.
The Innotox developers believe that liquid formulations will be easier to work with and avoid errors and loss of potency when reconstituting the lyophilisate and diluting the solution, as with other toxins that are presented in powder form.
Release form for 25 units, 50 units, 100 units.
Feature | Botulax | Innotox |
Type | Botulinum Toxin Type A Complex (Freeze-Dried) | Botulinum Toxin Type A Complex (Liquid) |
Form | Lyophilized powder (requires reconstitution) | Ready-to-use liquid formulation |
Stability | Stable when stored at low temperatures | More stable at room temperature |
Dilution | Requires saline dilution before use | No dilution needed, pre-mixed liquid |
Onset Time | 3-5 days | 3-4 days |
Duration | 4-6 months | 4-6 months |
Application | Facial wrinkles, hyperhidrosis, muscle relaxation | Facial wrinkles, hyperhidrosis, muscle relaxation |
Manufactured By | Hugel, South Korea | Medytox, South Korea |
Key Advantage | High purity and proven efficacy | No dilution required, reducing preparation error |
One of the most significant differences between Botulax and Innotox lies in their formulation.
Botulax is supplied as a lyophilized powder that requires reconstitution with saline before use. This is a common practice for many botulinum toxin products, ensuring stability during storage and transport. The reconstitution process, however, requires precision to achieve the correct concentration, which can sometimes be a drawback for less experienced practitioners.
Innotox, in contrast, is supplied as a ready-to-use liquid formulation. This is a groundbreaking advancement in the field of botulinum toxin products. The liquid form eliminates the need for reconstitution, reducing the risk of dosing errors and enhancing convenience for practitioners. This unique formulation of Innotox can lead to more consistent results and increased patient safety.
Onset of Action: Patients may notice the effects of Innotox slightly faster than Botulax, potentially due to its liquid formulation, which might facilitate quicker absorption.
Duration of Effect: Both products generally provide effects lasting between three to six months, though individual variations can occur. Some reports suggest that Innotox may have a marginally longer duration of effect, but more comparative studies are needed to confirm this.
In terms of safety, both products have been shown to have a favorable safety profile when administered by trained professionals. The most common side effects include localized pain, swelling, and bruising at the injection site. Severe adverse effects are rare but can include muscle weakness away from the injection site and allergic reactions.
Botulax and Innotox are two prominent botulinum toxin type A products with distinct characteristics that cater to various needs in the medical and aesthetic fields. Botulax, with its traditional lyophilized powder form, remains a reliable choice for practitioners familiar with the reconstitution process. Innotox, with its innovative liquid formulation, offers a convenient and potentially more consistent alternative.
Ultimately, the choice between Botulax and Innotox should be guided by the specific needs and preferences of the patient, as well as the experience and expertise of the practitioner. As the field of botulinum toxin therapy continues to evolve, both products are likely to remain integral tools in the arsenal of medical and aesthetic professionals worldwide.