Hyaluronic acid is a molecule that binds easily with water to keep the skin, joints, eyes and other connective tissues moisturized and lubricated. It has a low molecular weight, which means it can easily penetrate the skin.
It is best known as a moisturizer, and can help plump up skin to reduce fine lines and wrinkles. Because it is naturally found within the body, hyaluronic acid side effects are uncommon and occur most often as a result of the application method. It can be injected into the skin, or taken orally as a supplement.
Is Hyaluronic Acid Safe? Yes, because it is naturally found within the body. When combined with other substances, an allergic reaction may develop, but this substance on its own should not cause any adverse effects.
That said, there are two instances where supplementing with hyaluronic acid should be discouraged. First, for those with pre-existing conditions such as liver disease, as it may hinder a diagnosis. Second, in the case of injections, it may cause side effects for those who have a hypersensitive immune system.
Side effects will vary depending on the application method. Oral and topical use do not cause adverse reactions, however injections—such as in the case of dermal fillers—are more likely to do so, but only rarely as a result of the product itself.
When using any product for the first time, it is recommended to perform a patch test in a discreet area to determine any sensitivities.